Dixar Plus Syrup (20 mg+10 mg+2.5 mg)/5 ml 1 Pcs
Dextromethorphan + Phenylephrine + Triprolidine
This preparation is indicated for the symptomatic relief of upper respiratory tract disorders accompanied by non-productive cough which benefits from the administration of a nasal decongestant, a histamine H1-receptor antagonist and an antitussive combination.
This preparation is a mixture of antitussive, decongestant and antihistamine agent. Dextromethorphan is a safe, effective, non-narcotic antitussive agent which has a central action on the cough centre in the medulla. Although structurally related to Morphine, it has no analgesic and habit forming properties and in general it has little sedative activity. Phenylephrine is a decongestant that shrinks blood vessels in the nasal passage. It is used to treat nasal and sinus congestion of the tubes that drain fluid from inner ear. Triprolidine provides symptomatic relief in conditions believed to depend wholly or partly upon the triggered release of histamine. It is a potent competitive histamine H1-receptor antagonist of the pyrrolidine class with mild central nervous system depressant properties which may cause drowsiness.
Adults & Children over 12 years: 1 teaspoonful 4 times a day.
6-12 years: 1/2 teaspoonful 4 times a day.
A physician's advice should be obtained before administering this combination to children less than 6 years.
Take with or without food. Take with food if it causes an upset stomach. Measure liquid doses carefully. Use the measuring device that comes with this medicine.
This combination is contraindicated in patients with a known hypersensitivity to Dextromethorphan, Phenylephrine or Triprolidine as well as in persons under treatment with Monoamine Oxidase Inhibitor within 2 weeks of stopping such treatment.
Side effects of Dextromethorphan appears to be rare and may include drowsiness. Prostatic enlargement could have been an important predisposing factor.
Pregnancy & Lactation
There are no specific data on use of this combination during pregnancy & lactation
Precautions & Warnings
This combination may cause drowsiness. It may impair the patient’s ability to drive and also to use machineries. Although there are no objective data, users of this syrup should avoid the concomitant use of alcohol or other centrally acting sedatives. As with other sympathomimetic agents caution should be exercised in patients with hypertension, heart disease, diabetes, hyperthyroidism, elevated intraocular pressure and prostatic enlargement. This combination should not be used for persistent or chronic cough such as occurs with smoking, asthma, or emphysema or where cough is accompanied by excessive secretion unless directed by a physician.
Combined cough suppressants
Protect from light, store in a cool and dry place. Keep out of the reach of children.
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