Sodium Chloride + Dextrose
Dextrose + Sodium Chloride solution is indicated in Dehydration accompanied by small Sodium Chloride deficiency. It provides Dextrose as a nutrient in a suitable medium of Sodium Chloride. It is usually used in the maintenance and replacement of fluid, electrolyte and carbohydrate in patients who are unable to take fluid and nutrients by mouth e.g. in pre and post operative fluid regime, shock or accidents
Dextrose is a monosaccharide that is used as a source of calories and water for hydration. It helps to reduce loss of body protein and nitrogen. It also promotes glycogen deposition in the liver. When used with insulin, it stimulates the uptake of potassium by cells, especially in muscle tissue, thus lowering serum potassium levels.
Sodium chloride is the major extracellular cation. It is important in electrolyte and fluid balance, osmotic pressure control and water distribution as it restores sodium ions. It is used as a source of electrolytes and water for hydration, treatment of metabolic acidosis, priming solution in haemodialysis and treatment of hyperosmolar diabetes. It is also used as diluents for infusion of compatible drug additives.
Dosage & Administration
Dose is variable. Generally 60-120 drops/minutes are given intravenously or according to physician’s recommendation. Dose depends on the clinical condition, age and body surface area of the patients.
There are no known drug interactions and none well documented.
Febrile response, infection at the site of injection, venous thrombosis or phlebitis extending from the site of injection, extravasation and hypervolemia.
Pregnancy & Lactation
Pregnancy Category - C
Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks
Precautions & Warnings
As the preparation contains Sodium Chloride, it should be administered with caution to patients with congestive heart failure, peripheral or pulmonary oedema, impaired renal function or pre-eclampsia. Serum glucose concentration should also be carefully monitored and concurrent use of insulin may be needed in case of diabetic patients.
Infusion of fluid should be immediately discontinued if rigor arises for any reason during the process. Do not use if the solution is cloudy , contains particles, or after expiry date.
Intravenous fluid preparations
Should be stored at controlled room temperature.
- Type IV
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