Epam Tablet 5 mg - Click Pharma

Epam Tablet 5 mg 1 Pc

0.75 ৳
Generic Name:

Alternative products

Epam Tablet 5 mg

1 Pc
0.75 ৳




Short-term management of insomnia, Infantile spasms


Nitrazepam is a benzodiazepine with a pronounced sleep-inducing activity. It depresses the reticular-activating system in the brainstem by enhancing the inhibitory effect of GABA on brain cells, thus preventing excessive brain activity.



Short-term management of insomnia:

  • Adult: 5 mg at night; increase to 10 mg if necessary.
  • Elderly: and debilitated patients: ≤normal adult dose.

Infantile spasms:

  • Child: Infants: 125 mcg/kg bid; gradually increase to 250-500 mcg/kg bid.

* চিকিৎসকের পরামর্শ মোতাবেক ঔষধ সেবন করুন'


May be taken with or without food

* চিকিৎসকের পরামর্শ মোতাবেক ঔষধ সেবন করুন'


CNS depressant effect increased with alcohol, barbiturates, TCAs, phenothiazines, morphine derivatives. Effects may be antagonised by theophylline. Increased levels/effects with probenecid. Reduced levels/effects with rifampicin. May reduce effects of levodopa.


Myasthenia gravis, narrow-angle glaucoma, severe respiratory insufficiency, sleep apnoea syndrome, severe hepatic impairment, porphyria.


Side Effects

Hypotension, palpitation; agitation, aggressiveness, amnesia, ataxia, confusion, delusions, disorientation, dizziness, fatigue, hallucination, hangover, headache, irritability, nightmares, psychoses, rage, restlessness, sedation; rash; changes in libido; constipation, diarrhoea, excessive salivation, heartburn, nausea, vomiting; granulocytopenia, leukopenia; falling, muscle weakness; blurred or double vision; tinnitus (associated with withdrawal); aspiration, increased bronchial secretion, dyspnoea.

Pregnancy & Lactation

Category not classified

Precautions & Warnings

May induce anterograde amnesia; caution patients to have uninterrupted sleep of 7-8 hr after ingestion of dose. May impair ability to drive or operate machinery. Depression, especially if suicidal risk may be present. History of drug abuse or acute alcoholism. Hepatic and renal impairment. Respiratory disease. Debilitated patients. Patients who are at risk of falls. Children, elderly. Pregnancy and lactation.

Overdose Effects

Symptoms: Somnolence, drowsiness, confusion, ataxia, impaired reflexes, coma, dyspnoea, hypotension, respiratory and cardiovascular depression.

Management: Supportive. Gastric lavage may be beneficial if performed soon after ingestion. Flumazenil may reverse benzodiazepine-induced CNS depression.

Therapeutic Class

Benzodiazepine hypnotics

Storage Conditions

Store at room temperature. Protect from light and moisture.

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